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Human CA14/Carbonic Anhydrase XIV Protein (CA4-HM214)

Human CA14/Carbonic Anhydrase XIV Protein (CA4-HM214)

Item no.	CA4-HM214-500UG
Manufacturer	KactusBio
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Neuroscience Molecular Targets for Neuroscience
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	C-hFc
Purity	> 95% as determined by Bis-Tris PAGE
Dry ice	Yes
Sequence	Ala16-Met290
Alias	Carbonic anhydrase 14,EC:4.2.1.1,CA-XIV
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	CA14/Carbonic Anhydrase XIV
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 56.76 kDa. Due to glycosylation, the protein migrates to 65-85 kDa based on Bis-Tris PAGE result.
Description	Recombinant Human CA14/Carbonic Anhydrase XIV Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala16-Met290.
Background	Carbonic anhydrase XIV (CA XIV), a transmembrane protein, highly expressed in the central nervous system, is difficult to recombinantly express and purify in large scale for the measurements of inhibitor binding and drug design. CA XIV belongs to the family of twelve catalytically active CA isoforms in the human body. Disorders in the expression of CA XIV cause serious diseases and CA XIV has been described as a possible drug target for the treatment of epilepsy, some retinopathies, and skin tumors.
Endotoxin	Less than 0.1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20mM Tris, 150mM NaCl (pH 7.5).
Biotinylated	no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CA4-HM214-500UG-datasheet.pdf

CA4-HM214-500UG-safety-datasheet.pdf