HGF Antibody

Polyclonal Antibody

HGF

DFNB39 antibody, F TCF antibody, Fibroblast derived tumor cytotoxic factor antibody, Hepatocyte growth factor (hepapoietin A, scatter factor) antibody, Hepatocyte growth factor antibody, Hepatocyte growth factor beta chain antibody, Hepatocyte growth factor precursor antibody, Hepatopoietin A antibody, Hepatopoietin-A antibody, Hgf antibody, HGF_HUMAN antibody, HGFB antibody, HPTA antibody, Lung fibroblast derived mitogen antibody, OTTHUMP00000161349 antibody, OTTHUMP00000206710 antibody, OTTHUMP00000206711 antibody, OTTHUMP00000206712 antibody, OTTHUMP00000206713 antibody, OTTHUMP00000206730 antibody, Scatter factor antibody, SF antibody

Recombinant protein of human HGF

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Affinity-chromatography purified

Signal Transduction

Recombinant protein of Human HGF