Recombinant Human Heterogeneous nuclear ribonucleoprotein M(HNRNPM)

Epigenetics and Nuclear Signaling

Not Test

Homo sapiens (Human)

AAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGP KGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRY RAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRP LKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGM ITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANL DYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGI GTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER ALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPID ANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEG PFGGGMENMGRFGSGMNMGRINEILSNALKRGEII AKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGA GLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIER MGPLGLDHMASSIERMGQTMERIGSGVERMGAGMG FGLERMAAPIDRVGQTIERMGSGVERMGPAIERMG LSMERMVPAGMGAGLERMGPVMDRMATGLERMGAN NLERMGLERMGANSLERMGLERMGANSLERMGPAM GPALGAGIERMGLAMGGGGGASFDRAIEMERGNFG GSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTW KMLKDKFNECGHVLYADIKMENGKSKGCGVVKFES PEVAERACRMMNGMKLSGREIDVRIDRNA

2-730aa

93.4 kDa

Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinobryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

Greater than 90% as determined by SDS-PAGE.

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.

Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

N-terminal 6xHis-SUMO-tagged