Comparison

Recombinant Human Monoglyceride lipase(MGLL)

Manufacturer Cusabio
Category
Type Proteins
Specific against other
Amount 50ug
Host E.coli
Item no. CSB-EP013787HU-50
eClass 6.1 34160400
eClass 9.0 42020190
Available
Research Topic
Cardiovascular
Uniprot ID
Q99685
Gene Names
MGLL
Organism
Homo sapiens (Human)
AA Sequence
MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYW KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDL LVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD SMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFA GMVLISPLVLANPESATTFKVLAAKVLNLVLPNLS LGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFG IQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSK GAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTN SVFHEINMWVSQRTATAGTASPP
Expression Region
1-303aa
Sequence Info
Full Length
Source
E.coli
Tag Info
N-terminal GST-tagged
MW
60.3 kDa
Alternative Name
HU-K5
Lysophospholipase homolog
Lysophospholipase-like
Monoacylglycerol lipase
Relevance
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth
Reference
"A novel poxvirus gene and its human homolog are similar to an E. coli lysophospholipase."
Wall E.M., Cao J.X., Chen N., Buller R.M.L., Upton C.
Virus Res. 52:157-167(1997)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth
Subcellular Location
Cytoplasm, cytosol, Membrane, Peripheral membrane protein
Protein Families
AB hydrolase superfamily, Monoacylglycerol lipase family
Tissue Specificity
Detected in adipose tissue, lung, liver, kidney, brain and heart.
Amount: 50ug
Available: In stock
Listprice: €227.63
Price: €227.63
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