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Recombinant Human Molybdopterin synthase catalytic subunit(MOCS2)

Recombinant Human Molybdopterin synthase catalytic subunit(MOCS2)

Manufacturer	Cusabio
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	50ug
Host	E.coli
Item no.	CSB-EP014706HU-50
Conjugate/Tag	GST
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research Topic	Signal Transduction
Uniprot ID	O96007
Gene Names	MOCS2
Organism	Homo sapiens (Human)
AA Sequence	MSSLEISSSCFSLETKLPLSPPLVEDSAFEPSRKD MDEVEEKSKDVINFTAEKLSVDEVSQLVISPLCGA ISLFVGTTRNNFEGKKVISLEYEAYLPMAENEVRK ICSDIRQKWPVKHIAVFHRLGLVPVSEASIIIAVS SAHRAASLEAVSYAIDTLKAKVPIWKKEIYEESST WKGNKECFWASNS
Expression Region	1-188aa
Sequence Info	Full Length
Source	E.coli
Tag Info	N-terminal GST-tagged
MW	47.9 kDa
Alternative Name(s)	MOCO1-B Molybdenum cofactor synthesis protein 2 large subunit Molybdenum cofactor synthesis protein 2B
Relevance	Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Reference	"Human molybdopterin synthase gene: identification of a bicistronic transcript with overlapping reading frames." Stallmeyer B., Drugeon G., Reiss J., Haenni A.L., Mendel R.R. Am. J. Hum. Genet. 64:698-705(1999)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Involvement in disease	Molybdenum cofactor deficiency, complementation group B (MOCODB)
Subcellular Location	Cytoplasm, cytosol
Protein Families	MoaE family, MOCS2B subfamily
Tissue Specificity	Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.
Tag Information	N-terminal GST-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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