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Recombinant Human Myelin expression factor 2(MYEF2),partial

Recombinant Human Myelin expression factor 2(MYEF2),partial

Manufacturer	Cusabio
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins Astrocyte Markers
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	10ug
Host	E.coli
Item no.	CSB-EP015283HU-10
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research Topic	Transcription
Uniprot ID	Q9P2K5
Gene Names	MYEF2
Organism	Homo sapiens (Human)
AA Sequence	GGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYR GAMTSSMERDFGRGDIGINQGFGDSFGRLGSAMIG GFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMG LDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMG SGMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQC GHVMFAEIKMENGKSKGCGTVRFDSPESAE
Expression Region	372-576aa
Sequence Info	Partial
Source	E.coli
Tag Info	N-terminal 6xHis-SUMO-tagged
MW	37.3 kDa
Alternative Name(s)	MST156
Relevance	Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 elent 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA .
Reference	An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA (By similarity).
Subcellular Location	Nucleus
Tag Information	N-terminal 6xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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