Comparison

Recombinant Rat Atrial natriuretic peptide receptor 3(Npr3),partial

Manufacturer Cusabio
Category
Type Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Amount 1mg
Host E.coli
Item no. CSB-EP016025RA1-1
eClass 6.1 34160400
eClass 9.0 42020190
Available
Research Areas
Others
Uniprot ID
P41740
Gene Names
Npr3
Organism
Rattus norvegicus (Rat)
AA Sequence
EALAAQKIEVLVLLPRDDSYLFSLARVRPAIEYAL RSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFS LVDRVAAARGAKPDLILGPVCEYAAAPVARLASHW DLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMG EMMLALFRHHHWSRAALLYSDDKLERNCYFTLEGV HEVFQEEGLHTSAYNFDETKDLDLDDIVRYIQGSE RVVIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIE LFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLL RTAKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEG FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNR TFEGIAGQVSIDANGDRYGDFSVVAMTDTEAGTQE VIGDYFGKEGRFKMRSNVKYPWGSLKLRIDETRIV EHTNSSPCKSCGLEESA
Expression Region
41-477aa
Sequence Info
Extracellular Domain
Source
E.coli
Tag Info
N-terminal 6xHis-SUMO-tagged
MW
64.9 kDa
Alternative Name(s)
Atrial natriuretic peptide clearance receptorAtrial natriuretic peptide receptor type C ; ANP-C ; ANPR-C ; NPR-C
Relevance
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity .
Reference
A single residue determines the distinct pharmacology of rat and human natriuretic peptide receptor-C.Engel A.M., Schoenfeld J.R., Lowe D.G.J. Biol. Chem. 269:17005-17008(1994)
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Subcellular Location
Membrane, Single-pass type I membrane protein
Protein Families
ANF receptor family
Tag Information
N-terminal 6xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
available

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