Manufacturer |
Cusabio
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Amount |
500ug |
Host |
E.coli |
Item no. |
CSB-EP017946HU-500 |
Conjugate/Tag |
GST |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Research Topic |
Signal Transduction |
Uniprot ID |
O14832 |
Gene Names |
PHYH |
Organism |
Homo sapiens (Human) |
AA Sequence |
SGTISSASFHPQQFQYTLDNNVLTLEQRKFYEENG FLVIKNLVPDADIQRFRNEFEKICRKEVKPLGLTV MRDVTISKSEYAPSEKMITKVQDFQEDKELFRYCT LPEILKYVECFTGPNIMAMHTMLINKPPDSGKKTS RHPLHQDLHYFPFRPSDLIVCAWTAMEHISRNNGC LVVLPGTHKGSLKPHDYPKWEGGVNKMFHGIQDYE ENKARVHLVMEKGDTVFFHPLLIHGSGQNKTQGFR KAISCHFASADCHYIDVKGTSQENIEKEVVGIAHK FFGAENSVNLKDIWMFRARLVKGERTNL |
Expression Region |
1-338aa |
Sequence Info |
Full Length |
Source |
E.coli |
Tag Info |
N-terminal GST-tagged |
MW |
62.4 kDa |
Alternative Name(s) |
Phytanic acid oxidase Phytanoyl-CoA alpha-hydroxylase |
Relevance |
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. |
Reference |
"Identification of PAHX, a Refsum disease gene." Mihalik S.J., Morrell J.C., Kim D., Sachsteder K.A., Watkins P.A., Gould S.J. Nat. Genet. 17:185-189(1997) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. |
Involvement in disease |
Refsum disease (RD) |
Subcellular Location |
Peroxisome |
Protein Families |
PhyH family |
Tissue Specificity |
Expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. |
Tag Information |
N-terminal GST-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.