Comparison

Recombinant Human Ras-related protein R-Ras2(RRAS2)

Manufacturer Cusabio
Category
Type Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Amount 50ug
Host E.coli
Item no. CSB-EP020514HU-50
Conjugate/Tag GST
eClass 6.1 34160400
eClass 9.0 42020190
Available
Research Topic
Signal Transduction
Uniprot ID
P62070
Gene Names
RRAS2
Organism
Homo sapiens (Human)
AA Sequence
AAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQ SYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAG QEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYK FQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEE GQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIR KFQEQECPPSPEPTRKEKDKKGCHC
Expression Region
1-204aa
Sequence Info
Full Length
Source
E.coli
Tag Info
N-terminal GST-tagged
MW
49.9 kDa
Alternative Name(s)
Ras-like protein TC21
Teratocarcinoma oncogene
Relevance
It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Reference
"Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line."
Drivas G.T., Shih A., Coutavas E., Rush M.G., D'Eustachio P.
Mol. Cell. Biol. 10:1793-1798(1990)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Involvement in disease
Ovarian cancer (OC)
Subcellular Location
Cell membrane, Lipid-anchor, Cytoplasmic side
Protein Families
Small GTPase superfamily, Ras family
Tissue Specificity
Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
Paythway
cAMPsignalingpathway
Tag Information
N-terminal GST-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50ug
Available: In stock
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