Comparison

Recombinant Human Endothelial protein C receptor(PROCR) ,partial

Manufacturer Cusabio
Category
Type Proteins Recombinant
Specific against other
Amount 200ug
Host E.coli
Item no. CSB-RP063294h-200
eClass 6.1 34160400
eClass 9.0 42020190
Available
Research Topic
Cardiovascular
Uniprot ID
Q9UNN8
Gene Names
PROCR
Organism
Homo sapiens (Human)
AA Sequence
SQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGG HLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQ SYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPP EGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVT SGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQK HISAENTKGSQTSRSYTS
Expression Region
18-210aa
Sequence Info
Partial
Source
E.coli
Tag Info
N-terminal 6xHis-tagged
MW
26 kDa
Alternative Name(s)
Activated protein C receptor ; APC receptorEndothelial cell protein C receptor; CD201
Relevance
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Reference
Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor.Fukudome K., Esmon C.T.J. Biol. Chem. 269:26486-26491(1994)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Subcellular Location
Membrane, Single-pass type I membrane protein
Tissue Specificity
Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
Paythway
Complementandcoagulationcascades

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200ug
Available: In stock
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