ADAM10 ELISA Kits (for human, mouse, rat, rabbit)

Manufacturer Fivephoton
Category Products / ELISA
Type Elisa-Kit
Specific against Human, Mouse, Rat, Rabbit, Canine
Amount 96T
ArtNr pADAM10-ELISA(96T)
Eclass 6.1 32160605
Eclass 9.0 32160605
Available
Poisonous Material
Sodium Azide (0.1%)
Highlights
Fully pre-configured sandwich ELISA format providing technical convenience and high sensitivity. Assay ranges 10-1500pg/ml depending on species.
Strip plate configuration allowing separate use and storage of sections of the 96-well ELISA plate
Affinity purified polyclonal capture antibody on plate. Separate HRP-conjugated detection antibody.
Rapid assay with colorimetric detection (measure reaction at 450nm). Total incubation with ELISA plate and HRP antibody is 1 hr at 37C or 2 hr at RT.
As ADAM10 is a transmembrane protein, detergent cell lysis is required for isolation of the assay fraction.
Background
Members of the ADAM family are transmembrane proteins with a unique structure possessing both potential adhesion and protease domains. Sheddase, a generic name for the ADAM metallopeptidase, functions primarily to cleave membrane proteins at the cellular surface. Once cleaved, the sheddases release soluble ectodomains with an altered location and function.
Although a single sheddase may "shed" a variety of substances, multiple sheddases can cleave the same substrate resulting in different consequences. In neurons, ADAM10 is the most important enzyme with alpha-secretase activity for proteolytic processing of the amyloid precursor protein
Amount: 96T
Available: In stock
Listprice: €817.80
Discount: -10%
Price: €736.02
lieferbar

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