Antibodies

RAT ANTI HUMAN AID

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against Human
Applications WB
Amount 0.05 mg
Host Rat
ArtNr 20-783-314846
Available
Genway ID:
GWB-1DA251
Specificity:
AID
Isotype:
IgG2b
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3)Approx. Protein Concentrations: IgG concentration 1. 0 mg/ml
Immunogen:
Synthetic peptide corresponding to amino acids 185-198 of human AID.
Specificity:
Specifically recognizes human AID (Activation-induced cytidine deaminase) a 24kDa RNA-editing enzyme essential for the initiation of immunoglobulin class switch recombination (CSR) somatic hypermutation (SHM) and gene conversion (GC). Studies suggest that AID is selectively expressed by germinal centre (GC) B cells and B cell-derived lymphomas and that a deficiency in AID is responsible for the autosomal recessive form of the immunodeficient condition Hyper-IgM syndrome. Recommended Negative Controls: RAT IgG2b NEGATIVE CONTROLRecommended Secondary Antibodies: Goat Anti Rat IgGRabbit Anti Rat IgGGoat Anti Rat IgG (MOUSE ADSORBED)
Amount: 0.05 mg
Available: In stock
Listprice: €434.19
Price: €434.19
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