Antibodies

MOUSE ANTI HUMAN CD32

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against Human
Applications IP
Amount 0.02 mg
Host Mouse
ArtNr 20-783-314895
Available
Genway ID:
GWB-857E67
Specificity:
CD32
Isotype:
IgG1Species Cross Reactivity: Reacts with: Dog Rhesus Monkey PigN. B. Antibody reactivity and working conditions may vary between species.
Preparation:
Purified IgG prepared by affinity chromatography on Protein A
Preservative Stabilisers:
0. 09% Sodium AzideApprox. Protein Concentrations: IgG concentration 1 mg/ml
Immunogen:
K562 cell line
Specificity:
Recognises the human CD32 antigen a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis activation of secretion cytotoxicity and immunomodulation. CD32 is expressed by B cells monocytes granulocytes and platelets. Clone AT10 blocks the binding of IgG to Fc gamma RII (4). Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROLRecommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgG1Goat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L)
Function:
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Subunit structureInteracts with INPP5D/SHIP1 and INPPL1/SHIP2 regulating its function. Ref. 9Subcellular locationCell membrane; Single-pass type I membrane protein. Tissue specificityFound on monocytes neutrophils and eosinophil platelets. Sequence similaritiesContains 2 Ig-like C2-type (immunoglobulin-like) domains. Sequence cautionThe sequence AAA35932. 1 differs from that shown. Reason: Erroneous initiation.
Amount: 0.02 mg
Available: In stock
Listprice: €152.38
Price: €152.38
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