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MOUSE ANTI HUMAN CD32

MOUSE ANTI HUMAN CD32

Manufacturer	GENWAY
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Immunoprecipitation Primary Antibodies
Type	Antibody
Specific against	Human
Applications	IP
Amount	25 ug
Host	Mouse
Item no.	20-783-314895
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-857E67
Specificity:	CD32
Isotype:	IgG1Species Cross Reactivity: Reacts with: Dog Rhesus Monkey PigN. B. Antibody reactivity and working conditions may vary between species.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Preservative Stabilisers:		0. 09% Sodium AzideApprox. Protein Concentrations: IgG concentration 1 mg/ml
Immunogen:	K562 cell line
Specificity:	Recognises the human CD32 antigen a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis activation of secretion cytotoxicity and immunomodulation. CD32 is expressed by B cells monocytes granulocytes and platelets. Clone AT10 blocks the binding of IgG to Fc gamma RII (4). Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROLRecommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgG1Goat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L)
Function:	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Subunit structureInteracts with INPP5D/SHIP1 and INPPL1/SHIP2 regulating its function. Ref. 9Subcellular locationCell membrane; Single-pass type I membrane protein. Tissue specificityFound on monocytes neutrophils and eosinophil platelets. Sequence similaritiesContains 2 Ig-like C2-type (immunoglobulin-like) domains. Sequence cautionThe sequence AAA35932. 1 differs from that shown. Reason: Erroneous initiation.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ug

available

Delivery expected until 5/30/2024