Comparison

MOUSE ANTI HUMAN CD86:FITC

Manufacturer GENWAY
Category
Type Antibody
Specific against Human
Amount 25 ug
Host Mouse
Item no. 20-783-314903
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-B32334
Specificity:
CD86
Isotype:
IgG1
Preparation:
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 2
Preservative Stabilisers:
0. 09% Sodium Azide 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 1 mg/ml
Immunogen:
Human peripheral blood lymphocytes
Specificity:
Recognises the human CD86 antigen a cell surface protein expressed by activated B cells and monocytes. CD86 is also known as B7-2 and is the second ligand for CD28 and CTLA-4 and may have an important role in co-stimulation of T cells in the primary immune response. Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROL:FITC
Function:
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters and thus acts as a negative regulator of T-cell activation. Subunit structureInteracts with MARCH8. Interacts with human herpesvirus 8 MIR2 protein Probable. Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses. Ref. 11Ref. 12Subcellular locationMembrane; Single-pass type I membrane protein. Tissue specificityExpressed by activated B-lymphocytes and monocytes. Post-translational modificationPolyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation. Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
available

Delivery expected until 4/25/2024 

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