MOUSE ANTI HUMAN CD49a:FITC

Manufacturer GENWAY
Category
Type Antibody
Specific against Human
Amount 0.02 mg
Host Mouse
ArtNr 20-783-314905
Available
Genway ID:
GWB-B0FB85
Specificity:
CD49a
Isotype:
IgG1
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 1 mg/ml
Specificity:
Recognises the human alpha 1 integrin subunit which forms the VLA-1 heterodimer in association with the beta 1 integrin. VLA-1 is a receptor for collagen and laminin and is expressed by chronically activated T cells melanoma cells and smooth muscle cells. Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROL:FITC
Function:
Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Subunit structureHeterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1. Interacts with RAB21. Ref. 5Subcellular locationMembrane; Single-pass type I membrane protein.
Domain:
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. Sequence similaritiesBelongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain.
Amount: 0.02 mg
Available: In stock
Listprice: €182.24
Discount: -10.0%
Price: €164.02
You save: €18.22
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