Comparison

MOUSE ANTI HUMAN CD2

Manufacturer GENWAY
Category
Type Antibody
Specific against Human
Applications IP
Amount 0.02 mg
Host Mouse
Item no. 20-783-314912
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-5D5F00
Specificity:
CD2
Isotype:
IgG2bSpecies Cross Reactivity: Reacts with: Rhesus MonkeyN. B. Antibody reactivity and working conditions may vary between species.
Preparation:
Purified IgG prepared by affinity chromatography on Protein A.
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium AzideApprox. Protein Concentrations: IgG concentration 1 mg/ml
Immunogen:
Normal human peripheral blood lymphocytes.
Specificity:
Is a single chain transmembrane glycoprotein of 50kD expressed by T cells NK cells and thymocytes. CD2 is a receptor for CD58 (LFA-3) and is important in mediating the interaction between T cells and target cells or antigen presenting cells.
Specificity:
Inhibits NK cell mediated cytotoxicity and ConA and PHA mediated blast transformation. Recommended Negative Controls: MOUSE IgG2b NEGATIVE CONTROLRecommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGRabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgGGoat Anti Mouse IgG IgA IgMRabbit Anti Mouse IgGHuCAL Anti Mouse IgG2bGoat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L)
Function:
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells the cytoplasmic domain is implicated in the signaling function. Subunit structureInteracts with CD2AP By similarity. Interacts with PSTPIP1. Ref. 11Subcellular locationMembrane; Single-pass type I membrane protein. Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Bellingan. G. et al. (2002) Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation. J. Exp. Med. 196:1515-1521.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.02 mg
Available: In stock
available

Delivery expected until 4/25/2024 

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