Antibodies

RAT ANTI MOUSE Ly-6A/E:Biotin

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against Mouse
Applications WB, IP
Amount 0.1 mg
Host Rat
ArtNr 20-783-314725
Available
Genway ID:
GWB-4E2349
Specificity:
Ly-6A/E
Isotype:
IgG2a
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3) 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 5mg/ml
Immunogen:
IL-2-dependent mouse T cell line CTL-L.
Specificity:
Recognises members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically it recognises Ly-6A. 2 and Ly-6E. 1. Ly6-A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly-6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6. 1 and Ly-6. 2 allotypes. As such it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions it plays a role in bone formation myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells. Clone D7 has been reported to induce T cell activation. Recommended Secondary Antibodies: STREPTAVIDIN
Function:
T-cell activation. Subcellular locationCell membrane; Lipid-anchor & rsaquo; GPI-anchor. Tissue specificityWidely expressed. Ref. 10Ref. 11Post-translational modificationO-glycosylated. Not N-glycosylated. Ref. 9Not phosphorylated. Sequence similaritiesContains 1 UPAR/Ly6 domain.
Amount: 0.1 mg
Available: In stock
Listprice: €274.04
Price: €274.04
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