HAMSTER ANTI MOUSE BIM

Manufacturer GENWAY
Category
Type Antibody
Specific against Mouse
Applications IF
Amount 0.1 mg
Host Hamster
ArtNr 20-783-314811
Available
Genway ID:
GWB-2309B0
Specificity:
BIM
Isotype:
IgG
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3)Approx. Protein Concentrations: IgG concentration 1. 0mg/ml
Immunogen:
A complex of mouse BIM and Bcl-XL produced in insect cells.
Specificity:
Is specific for human Bcl-2 interacting mediator of cell death (Bim) also known as Bod. Bim is a pro-apoptotic protein within the Bcl-2 family which functions within the intrinsic apoptosis pathway. Bim is known to interact with pro-survival proteins including Bcl-2 Bcl-XL and Bcl-w. It is expressed in a variety of cell types where it is maintained in an inactive conformation by phosphorylation or through binding to the microtubule-associated dynein motor complex. Upon certain apoptotic stimuli Bim is released from microtubules and mediates caspase-dependent apoptosis. Recommended Negative Controls: HAMSTER (ARMENIAN) IgG NEGATIVE CONTROLRecommended Secondary Antibodies: Goat Anti Hamster IgG
Amount: 0.1 mg
Available: In stock
Listprice: €326.19
Discount: -10.0%
Price: €293.57
You save: €32.62
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