Antibodies

RAT ANTI MOUSE CD40:FITC

Manufacturer GENWAY
Category
Type Antibody
Specific against Mouse
Amount 0.02 mg
Host Rat
ArtNr 20-783-314906
Available
Genway ID:
GWB-4BBA05
Specificity:
CD40
Isotype:
IgG2a
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 1 mg/ml
Immunogen:
Extracellular Domain of Mouse CD40 and the Fc portion of Human IgG1
Specificity:
Specificity was checked by ELISA and flow cytometry using BHK cells transfected with mouse CD40. It does not react with normal mouse Ig or with human IgG1 and will stain most mature mouse B cells. It does not cross react with mouse T cells. Clone 3/23 is a powerful activator of normal B cells especially in the presence of IL-4. Recommended Negative Controls: RAT IgG2a NEGATIVE CONTROL:FITC
Function:
Receptor for TNFSF5/CD40LG. Subunit structureMonomer and homodimer. Interacts with TRAF1 TRAF2 and TRAF6 By similarity. Interacts with TRAF3 and TRAF5. Ref. 9Ref. 10Subcellular locationIsoform I: Cell membrane; Single-pass type I membrane protein. Isoform III: Cell membrane; Single-pass type I membrane protein. Isoform IV: Cell membrane; Single-pass type I membrane protein. Isoform V: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. Sequence similaritiesContains 4 TNFR-Cys repeats.
Amount: 0.02 mg
Available: In stock
Listprice: €182.24
Discount: -10.0%
Price: €164.02
You save: €18.22
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