« Back
Home /
FIBRONECTIN

FIBRONECTIN


Item no.	18-783-78954
Manufacturer	GENWAY
Amount	1 ml
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Cell Biology Cell Movement Cell Adhesion Western Blot ELISA Cell Stainings ECM Primary Antibodies
Type	Antibody
Applications	WB, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-8E7DE4
Similar products	18-783-78954
Available
Genway ID:	GWB-8E7DE4
Specificity:	FIBRONECTIN
Isotype:	Polyclonal IgG
Immunogen:	Purified murine fibronectin
Specificity Note:	This product recognises fibronectin a 460-500kD glycoprotein involved in tissue organisation and wound repair.
Preparation:	Ig fraction prepared by ammonium sulphate precipitation
Buffer Solution:	0. 05 M NH4HCO3
Preservative Stabilisers:		None present Reconstitution: Reconstitute in 1 ml of sterile distilled water. For long term storage the addition of a preservative is recommended. Suggested
Dilution:	Suggested
Dilution:	Western Blotting - 1/300 - 1/400
Function:	Fibronectins bind cell surfaces and various compounds including collagen fibrin heparin DNA and actin. Fibronectins are involved in cell adhesion cell motility opsonization wound healing and maintenance of cell shape.
Subunit:	Mostly heterodimers or multimers of alternatively spliced variants connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1 FBLN7 AMBP TNR LGALS3BP and COL13A1 (By similarity).
Subcellular Location:	Secreted extracellular space extracellular matrix.
Tissue Specificity:	Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms) made by fibroblasts epithelial and other cell types is deposited as fibrils in the extracellular matrix.
Ptm:	Sulfated (By similarity).
Ptm:	Forms covalent cross-links mediated by a transglutaminase such as F13A or TGM2 between a glutamine and the epsilon-amino group of a lysine residue forming homopolymers and heteropolymers (e. g. fibrinogen-fibronectin collagen-fibronectin heteropolymers).
Similarity:	Contains at least 2 fibronectin type-I domains. 1. Koya. D. et al. (2000) Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice. a rodent model for type 2 diabetes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 ml

available

Delivery expected until 11/27/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer