CD49e

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone JBS5
Applications FC, IP, IHC
Amount 0.025 mg
ArtNr 20-783-310029
Available
Genway ID:
GWB-90412D
Specificity:
CD49eNCBI
Gene ID:
3678
Specificity:
CD49e
Clone:
JBS5
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line. Histology: Human Endothelium
Preparation:
Purified IgG prepared by affinity chromatography on Protein G.
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul of whole blood. Suggested
Dilution:
Flow Cytometry - Neat - 1/10Immunohistology - Frozen - 0. 5ug/ml - 1ug/mlImmunoprecipitation - 1ug/ml - 5ug/ml
Function:
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi\' s sarcoma lesions.
Subunit:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the integrin alpha chain family.
Similarity:
Contains 7 FG-GAP repeats. 1. Shen. C. X. et al. (1991) Antibodies to different members of the beta 1 (CD29) Integrins induce homotypic and heterotypic cellular aggregation.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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