Antibodies

CD39

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone A1
Applications FC
Amount 25 TESTS
ArtNr 20-783-310045
Available
Genway ID:
GWB-7855BA
Specificity:
CD39NCBI
Gene ID:
953
Specificity:
CD39
Clone:
A1
Immunogen:
PHA activated human lymphocytes
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum Albumin
Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells or 100ul whole bloodSuggested
Dilution:
Flow Cytometry - Neat
Function:
In the nervous system could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.
Catalytic Activity:
ATP + 2 H2O = AMP + 2 phosphate. Cofactor: Calcium. Cofactor: Magnesium. Biophysicochemical Properties:
Subunit:
Homodimer; disulfide-linked (By similarity).
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Tissue Specificity:
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein whereas placental isoform I is present in placenta only.
Ptm:
The N-terminus is blocked.
Ptm:
Palmitoylated in the N-terminal part.
Similarity:
Belongs to the GDA1/CD39 NTPase family. 1. Aversa. G. G. et al. (1988) Detection of a late lymphocyte activation marker by A1. A new monoclonal antibody. 2. Waugh. J. A. et al. (1989) Staining of normal and rejecting kidney using the activation panel. In: Leucocyte Typing IV. White cell differentiation antigens. Edited by Knapp. W. et al. Oxford University Press. p485. 3. Aversa. G. G. and Hall. B. M. (1989) Activation panel antigen expression on PBL activated by PHA or in MLR. In: Leucocyte Typing IV. White cell differentiation antigens. Edited by Knapp. W. et al. Oxford University Press. p. 498. 4. Aversa. G. G. et al. (1989) Use of monoclonal antibodies to study in vivo and in vitro activated lymphocytes. 5. Stein. H. et al. (1989) Activated Section report. In: Leucocyte Typing IV. White cell differentiation antigens. Edited by Knapp. W. et al. Oxford University Press. p. 387. 6. Suranyi. M. G. et al. (1991) Lymphocyte adhesion molecules in T cell mediated lysis of kidney cells. Kidney International. 39: 312 - 3197. Stockl. J. et al. (2001) Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1 restricted. hapten-specific CTL.
Amount: 25 TESTS
Available: In stock
Listprice: €212.88
Price: €212.88
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