CD103


Manufacturer	GENWAY
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Hematology Leukemia Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies By Organ Bone Cancer
Type	Antibody
Specific against	other
Clone	LF61
Applications	FC
Amount	0.025 mg
Item no.	20-783-310084
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-BFE63B
Specificity:	CD103NCBI
Gene ID:	3682
Specificity:	CD103
Clone:	LF61
Immunogen:	Hairy cell leukaemia cells
Fusion Partner:	Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium Azide0. 5%Bovine Serum AlbuminSuggested
Flow Cytometry:	Use 5ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - Neat - 1/10
Function:	Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Subunit:	Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Domain:	The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Similarity:	Belongs to the integrin alpha chain family.
Similarity:	Contains 5 FG-GAP repeats.
Similarity:	Contains 1 VWFA domain. 1. Flenghi. L. et al. (1990) LF61: a new monoclonal antibody directed against a trimeric molecule (150kD. 125kD. 105kD) associated with hairy cell leukaemia. Br. J. Haem. 76: 451-459. 2. Falini. B. et al. (1990) Selection of a panel of monoclonal antibodies for monitoring residual disease in peripheral blood and bone marrow of interferon-treated hairy cell leukaemia patients.

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Amount: 0.025 mg

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Delivery expected until 5/30/2024