Antibodies

CD103

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone LF61
Applications FC
Amount 0.025 mg
ArtNr 20-783-310084
Available
Genway ID:
GWB-BFE63B
Specificity:
CD103NCBI
Gene ID:
3682
Specificity:
CD103
Clone:
LF61
Immunogen:
Hairy cell leukaemia cells
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium Azide0. 5%Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 5ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat - 1/10
Function:
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Subunit:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Domain:
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Similarity:
Belongs to the integrin alpha chain family.
Similarity:
Contains 5 FG-GAP repeats.
Similarity:
Contains 1 VWFA domain. 1. Flenghi. L. et al. (1990) LF61: a new monoclonal antibody directed against a trimeric molecule (150kD. 125kD. 105kD) associated with hairy cell leukaemia. Br. J. Haem. 76: 451-459. 2. Falini. B. et al. (1990) Selection of a panel of monoclonal antibodies for monitoring residual disease in peripheral blood and bone marrow of interferon-treated hairy cell leukaemia patients.
Amount: 0.025 mg
Available: In stock
Listprice: €182.24
Price: €182.24
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