Antibodies

CD182

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone HC2
Applications FC
Amount 25 TESTS
ArtNr 20-783-310099
Available
Genway ID:
GWB-CE2C7F
Specificity:
CD182NCBI
Gene ID:
3579
Specificity:
CD182
Clone:
HC2
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum Albumin
Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells or 100ul whole bloodSuggested
Dilution:
Flow Cytometry - Neat
Function:
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3 GRO/MGSA and NAP-2.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Ptm:
Phosphorylated upon ligand binding; which is required for desensitization.
Similarity:
Belongs to the G-protein coupled receptor 1 family [view classification]. 1. Petering. H. et al. (1999) The Biologic Role of Interleukin-8: Functional Analysis and Expression of CXCR1 and CXCR2 on Human Eosinophils. 2. Zahn. S. et al. (1997) Chemoattractant receptors for interleukin-8 and C5a: expression on peripheral blood leukocytes and differential regulation on HL-60 and AML-193 cells by vitamin D3 and all-trans retinoic acid.
Amount: 25 TESTS
Available: In stock
Listprice: €212.88
Discount: -10.0%
Price: €191.59
You save: €21.29
lieferbar

Get an offer

Technische Fragen zu diesem Produkt?


Salesmanager: Arne Pelz

Email: sales@hoelzel.de

Close