Comparison

INTEGRIN ALPHA 9 BETA 1

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone Y9A2
Applications FC, IP
Amount 0.025 mg
Item no. 20-783-310118
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-F161F0
Specificity:
INTEGRIN ALPHA 9 BETA 1NCBI
Gene ID:
3680
Specificity:
INTEGRIN ALPHA 9 BETA 1
Clone:
Y9A2
Immunogen:
alpha9 integrin transfected lambda cells.
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106cells in 100ul.
Function:
Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin.
Subunit:
Heterodimer of an alpha and a beta subunit. Alpha-9 associates with beta-1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
In airway epithelium in the basal layer of squamous epithelium and in smooth muscle skeletal muscle and hepatocytes. Abundantly expressed in fetal lung and lung cancers.
Induction:
Up-regulated in small cell lung cancers (SCLC).
Similarity:
Belongs to the integrin alpha chain family.
Similarity:
Contains 7 FG-GAP repeats. 1. Wang. A. et al. (1996) Differential regulation of airway epithelial integrins by growth factors. 2. Smith. L. L. et al. (1996) Osteopontin N-terminal domain contains a cryptic adhesive sequence recognised by alpha9 beta1 integrin. 3. Yokosaki. Y. et al. (1996) Differential effects of the integrins alpha9 beta1. alphaV/beta3 and alphaV beta6 on cell proliferative responses to tenascin. J. Biol. Chem. 271: 24144-24150.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.025 mg
Available: In stock
available

Delivery expected until 4/25/2024 

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