CD31


Manufacturer	GENWAY
Category	Oncology Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies By Organ Lung Cancer
Type	Antibody
Specific against	other
Clone	LCI-4
Applications	FC
Amount	25 TESTS
Item no.	20-783-310144
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-DE2542
Specificity:	CD31NCBI
Gene ID:	396941
Isotype:	IgG1
Clone:	LCI-4
Immunogen:	Porcine CD31/human IgGFc fusion protein
Specificity:	Recognises porcine CD31 a 140kD cell surface also celled PECAM-1. CD31 is expressed by various cell types but particularly by endothelial cells. Clone LCL-4 has been shown to stimulate tyrosine phosphorylation of CD31 on endothelial cells.
Preparation:	Purified IgG prepared by affinity chromatography from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09% Sodium Azide Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 100ul of lysed whole blood or 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - Neat
Function:	This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Long isoform predominates all tissues examined isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
Ptm:	Phosphorylated on Ser and Tyr residues after cellular activation.
Similarity:	Contains 6 Ig-like C2-type (immunoglobulin-like) domains. 1. Evans. P. C. et al. (2001) Signaling through CD31 protects endothelial cells from apoptosis.

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Amount: 25 TESTS

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Delivery expected until 5/9/2024