Antibodies

CD31

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone LCI-4
Applications FC
Amount 25 TESTS
ArtNr 20-783-310144
Available
Genway ID:
GWB-DE2542
Specificity:
CD31NCBI
Gene ID:
396941
Isotype:
IgG1
Clone:
LCI-4
Immunogen:
Porcine CD31/human IgGFc fusion protein
Specificity:
Recognises porcine CD31 a 140kD cell surface also celled PECAM-1. CD31 is expressed by various cell types but particularly by endothelial cells. Clone LCL-4 has been shown to stimulate tyrosine phosphorylation of CD31 on endothelial cells.
Preparation:
Purified IgG prepared by affinity chromatography from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09% Sodium Azide
Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 100ul of lysed whole blood or 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat
Function:
This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Long isoform predominates all tissues examined isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
Ptm:
Phosphorylated on Ser and Tyr residues after cellular activation.
Similarity:
Contains 6 Ig-like C2-type (immunoglobulin-like) domains. 1. Evans. P. C. et al. (2001) Signaling through CD31 protects endothelial cells from apoptosis.
Amount: 25 TESTS
Available: In stock
Listprice: €212.88
Price: €212.88
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