CD252

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone OX-89
Applications FC, IHC
Amount 0.025 mg
ArtNr 20-783-310190
Available
Genway ID:
GWB-4022D7
Specificity:
CD252NCBI
Gene ID:
22164
Specificity:
CD252
Clone:
OX-89
Immunogen:
Rat CD4 and mouse CD134 ligand Chimaeric protein
Fusion Partner:
Spleen cells from immunised PVG rats were fused with cells of the NS1 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Function:
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Subunit:
Homotrimer (Probable).
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Induction:
By human T-cell leukemia virus type I transactivator P40-TAX.
Disease:
Genetic variation in TNFSF4 influences susceptibility to systemic lupus erythematosus (SLE) [MIM:152700]. SLE is a chronic inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin joints kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Similarity:
Belongs to the tumor necrosis factor family. 1. Malstrom. V. et al (2001) CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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