Antibodies

CD115

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone 604B5 2E11
Applications FC
Amount 0.025 mg
ArtNr 20-783-310191
Available
Genway ID:
GWB-7B72EE
Specificity:
CD115NCBI
Gene ID:
12978
Specificity:
CD115
Clone:
604B5 2E11
Immunogen:
Raw 264 cells
Fusion Partner:
Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653 myeloma cell line.
Preparation:
Purified IgG prepared by ion exchange chromatography
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1/25 - 1/50
Function:
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
Catalytic Activity:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit:
Interacts with INPPL1/SHIP2 and THOC5 (By similarity).
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed in bone marrow and in differentiated blood mononuclear cells.
Similarity:
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Similarity:
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Similarity:
Contains 1 protein kinase domain. 1. Shadduck. R. K. et al. (1996) Paradoxical stimulation of normal and leukemic rat hematopoiesis by monoclonal antibody to CSF-I receptor. 2. Gilmore. G. L. et al. (1995) Inhibition of day-12 spleen colony-forming units by a monoclonal antibody to the murine macrophage/monocyte colony-stimulating factor receptor. 3. MacDonald. K. P. A. et al. (2005) The colony stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion.
Amount: 0.025 mg
Available: In stock
Listprice: €177.85
Price: €177.85
lieferbar

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