Antibodies

CD122

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone MIK-beta 1
Applications FC
Amount 0.025 mg
ArtNr 20-783-310200
Available
Genway ID:
GWB-F76AFD
Specificity:
CD122NCBI
Gene ID:
3560
Specificity:
CD122
Clone:
MIK-beta 1
Preparation:
Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:
Tris buffered saline
Preservative Stabilisers:
0. 01%ThimerosalSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells or 100ul of whole blood. Suggested
Dilution:
Flow Cytometry - 1/10 - 1/50
Function:
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Subunit:
Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer an intermediate affinity monomer (beta chain) and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Domain:
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
Domain:
The box 1 motif is required for JAK interaction and/or activation.
Similarity:
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Similarity:
Contains 1 fibronectin type-III domain. 1. Tsudo. M. et al. (1989) Characterization of the interleukin-2 receptor beta chain using three distinct monoclonal antibodies.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Price: €152.38
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