CD49c

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone 17C6
Applications FC, IHC
Amount 0.025 mg
ArtNr 20-783-310202
Available
Genway ID:
GWB-907200
Specificity:
CD49cNCBI
Gene ID:
3675
Specificity:
CD49c
Clone:
17C6
Immunogen:
CD49c transfected cell line
Fusion Partner:
Cells from immunised Balb/c mice were fused with cells of the NS2 mouse myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1/25 - 1/50
Function:
Integrin alpha-3/beta-1 is a receptor for fibronectin laminin collagen epiligrin thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Subunit:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-3 associates with beta-1. Interacts with HPS5.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain both isoforms are exclusively expressed on vascular smooth muscle cells whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells isoform alpha-3B is detected only on endothelial vein cells.
Ptm:
Isoform alpha-3A but not isoform alpha-3B is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
Similarity:
Belongs to the integrin alpha chain family.
Similarity:
Contains 7 FG-GAP repeats.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
lieferbar

Get an offer

Technische Fragen zu diesem Produkt?


Salesmanager: Arne Pelz

Email: sales@hoelzel.de

Close