CD180


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	MHR73
Applications	FC, IP, IHC
Amount	0.025 mg
Item no.	20-783-310254
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-9F2F9C
Specificity:	CD180NCBI
Gene ID:	4064
Specificity:	CD180
Clone:	MHR73
Immunogen:	M12HRP cell line.
Fusion Partner:	Spleen cells from immunised Balb/c mice were fused with cells of the SP2/0 myeloma cell line. Histology: Tonsil
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - 1/50 - 1/100
Function:	May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Subunit:	Binds to MD-1.
Subcellular Location:	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:	Expressed mainly on mature peripherical B cells. Detected in spleen lymph node and appendix. Not detected in pre-B and -T cells.
Disease:	Decreased expression of LY64 has been shown in systemic lupus erythematosus (SLE). The loss of LY64 is associated with B-cell activation and increased disease activity in SLE patients.
Similarity:	Belongs to the Toll-like receptor family.
Similarity:	Contains 17 LRR (leucine-rich) repeats. 1. Miura. Y. et al. (1998) RP105 is associated with MD-1 and transmits an activation signal in human B cells.

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Amount: 0.025 mg

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Delivery expected until 5/30/2024