CD206

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone 15-2
Applications WB, FC, IHC
Amount 0.025 mg
ArtNr 20-783-310260
Available
Genway ID:
GWB-9D05BB
Specificity:
CD206NCBI
Gene ID:
4360
Specificity:
CD206
Clone:
15-2
Immunogen:
Purified human mannose receptor
Fusion Partner:
Spleen cells from immunised Balb/c mice where fused with cells of the SP2/0 Ag. 14 mouse myeloma cell line.
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Function:
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria fungi and other pathogens.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Miscellaneous:
CRDs 1-3 have at most very weak affinity for carbohydrate. CRD 4 shows the highest affinity binding and has multispecificity for a variety of monosaccharides. At least 3 CRDs (4 5 and 7) are required for high affinity binding and endocytosis of multivalent glycoconjugates.
Similarity:
Contains 8 C-type lectin domains.
Similarity:
Contains 1 fibronectin type-II domain.
Similarity:
Contains 1 ricin B-type lectin domain. 1. Barrett-Bergshoeff. M. et al. (1997) Monoclonal antibodies against the human mannose receptor that inhibit the binding of tissue-type plasminogen activator.
Amount: 0.025 mg
Available: In stock
Listprice: €258.32
Discount: -10.0%
Price: €232.49
You save: €25.83
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