Comparison

CD14

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone MEM-18
Applications WB, FC, IP, ELISA
Amount 0.025 mg
Item no. 20-783-310268
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-265CE4
Specificity:
CD14NCBI
Gene ID:
929
Specificity:
CD14
Clone:
MEM-18
Fusion Partner:
Spleen cells from mice immunised BALB/c mice were fused with cells from the NS1-Ag4/1 mouse myeloma line.
Preparation:
Purified IgG prepared by DEAE - Chromatogaphy
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Western Blotting - Non-reducing conditions
Function:
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88 TIRAP and TRAF6 leading to NF-kappa-B activation cytokine secretion and the inflammatory response. Up-regulates cell surface molecules including adhesion molecules.
Subunit:
Belongs to the lipopolysaccharide (LPS) receptor a multi-protein complex containing at least CD14 MD-2 and TLR4.
Subcellular Location:
Cell membrane; Lipid-anchor GPI-anchor.
Tissue Specificity:
Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Similarity:
Contains 11 LRR (leucine-rich) repeats. 1. Pltz. S. G. et al. (2001) The interaction of human peripheral blood eosinophils with bacterial lipopolysacchride is CD14 dependent. Blood. 97: 235 - 241. 2. Prager. E. et al. (2001) Induction of Hyporesponsiveness and Impaired T lymphocyte activation by the CD31 receptor: ligand pathway in T cells. 3. Thacker. E. et al. (2001) Summary of workshop findings for porcine myelomonocytic markers.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.025 mg
Available: In stock
available

Delivery expected until 4/25/2024 

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