Comparison

CD101

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone BB27
Applications FC
Amount 0.025 mg
Item no. 20-783-310289
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-A5AD43
Specificity:
CD101NCBI
Gene ID:
9398
Specificity:
CD101
Clone:
BB27
Immunogen:
Human thymic clone B12
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cell in 100ul. Suggested
Dilution:
Flow Cytometry - 1/5 - 1/10
Function:
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Expressed in lung thymus and small intestine. Detected in cutaneous dendritic cells activated T-cells monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells the CD4(+) CD56(+) blastic tumor cells as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.
Ptm:
N-glycosylated.
Similarity:
Contains 7 Ig-like C2-type (immunoglobulin-like) domains. 1. Bagot. M. et al. (1997) CD101 is expressed by skin dendritic cells. Role in T-lymphocyte activation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.025 mg
Available: In stock
available

Delivery expected until 4/25/2024 

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