KIR

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone NKVFS1
Applications FC
Amount 0.025 mg
ArtNr 20-783-310294
Available
Genway ID:
GWB-BA36B0
Specificity:
KIRNCBI
Gene ID:
3802
Specificity:
KIR
Clone:
NKVFS1
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat - 1/5
Function:
Could be a regulatory protein possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Subunit:
Interacts with calmodulin in a Ca(2+)-dependent manner. Binds ROCK1.
Subcellular Location:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity:
Most abundant in thymus spleen kidney lung and testis. Less abundant in heart brain liver and skeletal muscle.
Induction:
By mitogens.
Ptm:
Phosphorylated on tyrosine residues.
Similarity:
Belongs to the small GTPase superfamily. RGK family. 1. Spaggiari. G. M. et al. (2002) Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: evidence for a negative regulation exerted by members of the inhibitory receptor superfamily. 2. Spaggiari. G. M. et al. (2002) Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction.
Amount: 0.025 mg
Available: In stock
Listprice: €182.24
Discount: -10.0%
Price: €164.02
You save: €18.22
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