Antibodies

CD210

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone 1B1. 3a
Applications FC
Amount 25 TESTS
ArtNr 20-783-310304
Available
Genway ID:
GWB-AA2410
Specificity:
CD210NCBI
Gene ID:
16154
Specificity:
CD210
Clone:
1B1. 3a
Immunogen:
Purified recombinant extracellular region of mouse CD210
Fusion Partner:
Spleen cells from immunised Fisher rats were fused with cells of the mouse SP2/0 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum Albumin
Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (/). Due to low expression of CDw210a. sensitive staining techniques may be required. Suggested
Dilution:
Flow Cytometry - Neat - 1/10
Function:
Receptor for IL10; binds IL10 with a high affinity.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Spleen thymus and PBMC. Weak expression in pancreas skeletal muscle brain heart and kidney. Placenta lung and liver showed intermediate levels. Monocytes B-cells large granular lymphocytes and T-cells express high levels.
Similarity:
Belongs to the type II cytokine receptor family. 1. Asseman C. et al. (1999) An essential role for Interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. 2. Phillips J. et al. (2001) Cutting edge: Interactions through the IL - 10 receptor regulate autoimmune diabetes. 3. Sundstedt A. et al. (2003) Role for IL - 10 in suppression mediated by peptide - induced regulatory T cells in vivo.
Amount: 25 TESTS
Available: In stock
Listprice: €258.32
Price: €258.32
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