CD210


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Lung Cancer
Type	Antibody
Specific against	other
Clone	1B1. 3a
Applications	FC
Amount	25 TESTS
Item no.	20-783-310304
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-AA2410
Specificity:	CD210NCBI
Gene ID:	16154
Specificity:	CD210
Clone:	1B1. 3a
Immunogen:	Purified recombinant extracellular region of mouse CD210
Fusion Partner:	Spleen cells from immunised Fisher rats were fused with cells of the mouse SP2/0 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide1%Bovine Serum Albumin Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 1x 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (/). Due to low expression of CDw210a. sensitive staining techniques may be required. Suggested
Dilution:	Flow Cytometry - Neat - 1/10
Function:	Receptor for IL10; binds IL10 with a high affinity.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Spleen thymus and PBMC. Weak expression in pancreas skeletal muscle brain heart and kidney. Placenta lung and liver showed intermediate levels. Monocytes B-cells large granular lymphocytes and T-cells express high levels.
Similarity:	Belongs to the type II cytokine receptor family. 1. Asseman C. et al. (1999) An essential role for Interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. 2. Phillips J. et al. (2001) Cutting edge: Interactions through the IL - 10 receptor regulate autoimmune diabetes. 3. Sundstedt A. et al. (2003) Role for IL - 10 in suppression mediated by peptide - induced regulatory T cells in vivo.

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Amount: 25 TESTS

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Delivery expected until 5/30/2024