Antibodies

CD49e

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone MFR5 (5H10)
Applications FC, IHC
Amount 0.025 mg
ArtNr 20-783-310346
Available
Genway ID:
GWB-79E3DD
Specificity:
CD49eNCBI
Gene ID:
16402
Specificity:
CD49e
Clone:
MFR5 (5H10)
Immunogen:
Mouse MC/9 cell line
Fusion Partner:
Spleen cells from immunised Lewis rats were fused with cells of the Murine P3X63Ag8. 653
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ml. Suggested
Dilution:
Flow Cytometry - 1/10 - 1/25
Function:
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi\' s sarcoma lesions.
Subunit:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the integrin alpha chain family.
Similarity:
Contains 7 FG-GAP repeats. 1. Kinashi. T. and Springer. T. A. (1994) Adhesion Molecules in Hematopoietic cells. 2. Van der Loo. J. C. M. et al. (1998) VLA-5 Is Expressed by Mouse and Human Long-term Repopulating Hematopoietic Cells and Mediates Adhesion to Extracellular Matrix Protein Fibronectin. 3. Cukierman. E. et al. (2001) Taking Cell-Matrix adhesions to the Third Dimension.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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