Antibodies

CD121a

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone JAMA-147
Applications FC, IP
Amount 0.025 mg
ArtNr 20-783-310399
Available
Genway ID:
GWB-509D63
Specificity:
CD121aNCBI
Gene ID:
16177
Specificity:
CD121a
Clone:
JAMA-147
Immunogen:
Extracellular domain of murine IL-1R.
Fusion Partner:
Spleen cells from immunised Armenian Hamster were fused with cells of the mouse P3X63. Ag 8-653 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1/25 - 1/100
Function:
Receptor for interleukin-1 alpha (IL-1A) beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP TOLLIP MYD88 and IRAK1 or IRAK2.
Subunit:
Binds IL1RAP.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the interleukin-1 receptor family.
Similarity:
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Similarity:
Contains 1 TIR domain. 1. Rogers. H. W. et al. (1992) Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Price: €152.38
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