CD121a


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Immunoprecipitation Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	JAMA-147
Applications	FC, IP
Amount	0.025 mg
Item no.	20-783-310399
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-509D63
Specificity:	CD121aNCBI
Gene ID:	16177
Specificity:	CD121a
Clone:	JAMA-147
Immunogen:	Extracellular domain of murine IL-1R.
Fusion Partner:	Spleen cells from immunised Armenian Hamster were fused with cells of the mouse P3X63. Ag 8-653 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - 1/25 - 1/100
Function:	Receptor for interleukin-1 alpha (IL-1A) beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP TOLLIP MYD88 and IRAK1 or IRAK2.
Subunit:	Binds IL1RAP.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Similarity:	Belongs to the interleukin-1 receptor family.
Similarity:	Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Similarity:	Contains 1 TIR domain. 1. Rogers. H. W. et al. (1992) Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice.

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Amount: 0.025 mg

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Delivery expected until 5/9/2024