GITRL

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone YGL386
Applications FC
Amount 0.025 mg
ArtNr 20-783-310467
Available
Genway ID:
GWB-41CCC0
Specificity:
GITRL
Specificity:
GITRL
Clone:
YGL386
Immunogen:
Recombinant mouse GITRL
Fusion Partner:
Spleen cells from immunised DA rats were fused with cells of the Y3/Ag1. 2. 3 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1/25 - 1/50
Function:
Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.
Subunit:
Homotrimer (Potential).
Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).
Tissue Specificity:
Expressed at high levels in the small intestine ovary testis kidney and endothelial cells.
Induction:
Up-regulated after stimulation by lipopolysaccharides.
Similarity:
Belongs to the tumor necrosis factor family. 1. Cobbold. S. P. et al. (2004) Induction of FoxP3+ Regulatory T Cells in the Periphery of T cell Receptor Transgenic mice Tolerized to Transplants. 2. ? (0) 1) Cobbold. S. P. et al. (2004). Induction of FoxP3+ Regulatory T Cells in the Periphery of T cell Receptor Transgenic mice Tolerized to Transplants.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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