Antibodies

CD88

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone 33878
Applications FC
Amount 25 TESTS
ArtNr 20-783-310480
Available
Genway ID:
GWB-187C47
Specificity:
CD88
Specificity:
CD88
Clone:
33878
Immunogen:
RBL-2H3 transfected cells expressing murine C5aR
Fusion Partner:
Cells from immunised Lou/c rats were fused with cells of the X63-Ag8. 653 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum Albumin
Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (//). Suggested
Dilution:
Flow Cytometry - Neat
Function:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis granule enzyme release and superoxide anion production.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Ptm:
Sulfation plays a critical role in the association of the receptor with C5a but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
Similarity:
Belongs to the G-protein coupled receptor 1 family [view classification]. 1. Soruri. A. et al. (2003) Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody.
Amount: 25 TESTS
Available: In stock
Listprice: €212.88
Price: €212.88
lieferbar

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