CD80

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone RM80
Applications FC
Amount 0.025 mg
ArtNr 20-783-310492
Available
Genway ID:
GWB-34DE94
Specificity:
CD80NCBI
Gene ID:
12519
Specificity:
CD80
Clone:
RM80
Immunogen:
BCL1 cells expressing CD80
Fusion Partner:
Spleen cells from immunised SD rats were fused with cells of the P3U1 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Suggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (/). Suggested
Dilution:
Flow Cytometry - Neat
Function:
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
Subunit:
Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed on activated B-cells macrophages and dendritic cells.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Nuriya. S. et al. (1996) The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity. 2. Jin. L-P et al. (2004) Adoptive transfer of paternal antigen-hyporesponsive T cells induces maternal tolerance to the allogeneic fetus in abortion-prone matings. 3. Nakajima. A. et al. (1997) Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells. 4. Nozawa. K. et al. (2001) Preferential blockade of CD8+ T cell responses by administration of anti-CD137 ligand monoclonal antibody results in differential effect on development of murine acute and chronic graft-versus-host diseases.
Amount: 0.025 mg
Available: In stock
Listprice: €202.38
Discount: -10.0%
Price: €182.14
You save: €20.24
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