CD21

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone Bu33
Applications FC
Amount 0.025 mg
ArtNr 20-783-310533
Available
Genway ID:
GWB-1FF4A5
Specificity:
CD21
Specificity:
CD21
Clone:
Bu33
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide (NaN3) Suggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1/50 - 1/200
Function:
Receptor for complement C3Dd for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Mature B-lymphocytes T-lymphocytes pharyngeal epithelial cells astrocytes and follicular dendritic cells of the spleen.
Disease:
Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin joints kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Similarity:
Belongs to the receptors of complement activation (RCA) family.
Similarity:
Contains 15 Sushi (CCP/SCR) domains. 1. Oxford University Press. (1997) Leucocyte Typing III. p58 - 602. Garland Publishing. Inc. (1998) Leucocyte Typing VI. p 140 1423. Thornton. C. A. et al. (2002) Expression of CD21 and CD23 during human fetal development. 4. Mayall. S. et al. (0) The anti-human CD21 antibody. BU33. identifies equine B cells.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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