CD74


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	Bu45
Applications	FC
Amount	0.025 mg
Item no.	20-783-310537
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-26C773
Specificity:	CD74
Specificity:	CD74
Clone:	Bu45
Immunogen:	B lymphoblastoid cell line HFB1.
Fusion Partner:	Spleen cells from immunised mice were fused with cells of the Ag8. 653 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Suggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - Neat - 1/5
Function:	Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
Subunit:	Nonamer composed of three alpha/beta/gamma heterotrimers.
Subcellular Location:	Membrane; Single-pass type II membrane protein (Potential).
Similarity:	Contains 1 thyroglobulin type-1 domain. 1. Wraight. C. J. et al. (1990) Human major histocompatibility complex class II invariant chain is expressed on the cell surface.

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Amount: 0.025 mg

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Delivery expected until 5/9/2024