CD85a


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	4F9
Applications	FC
Amount	0.025 mg
Item no.	20-783-310559
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-106D0D
Specificity:	CD85a
Specificity:	CD85a
Clone:	4F9
Immunogen:	Monocyte derived dendritic cells
Fusion Partner:	Spleen cells from immunised Balb/c mice were fused with cells of the mouse X63-Ag8. 653 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Suggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - Neat - 1/10
Function:	May act as receptor for class I MHC antigens.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Detected in monocytes and B-cells.
Domain:	Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Miscellaneous:	Belongs to the leukocyte receptor cluster (LRC) present on 19q13. 4.
Similarity:	Contains 4 Ig-like C2-type (immunoglobulin-like) domains. 1. Colonna. M. et al. (1999) A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. 2. Borges. L. et al. (1997) A family of human lymphoid and myeloid Ig-like receptors. some of which bind to MHC class I molecules.

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Amount: 0.025 mg

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Delivery expected until 5/9/2024