CD85a

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone 4F9
Applications FC
Amount 0.025 mg
ArtNr 20-783-310559
Available
Genway ID:
GWB-106D0D
Specificity:
CD85a
Specificity:
CD85a
Clone:
4F9
Immunogen:
Monocyte derived dendritic cells
Fusion Partner:
Spleen cells from immunised Balb/c mice were fused with cells of the mouse X63-Ag8. 653 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Suggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat - 1/10
Function:
May act as receptor for class I MHC antigens.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Detected in monocytes and B-cells.
Domain:
Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Miscellaneous:
Belongs to the leukocyte receptor cluster (LRC) present on 19q13. 4.
Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains. 1. Colonna. M. et al. (1999) A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. 2. Borges. L. et al. (1997) A family of human lymphoid and myeloid Ig-like receptors. some of which bind to MHC class I molecules.
Amount: 0.025 mg
Available: In stock
Listprice: €182.24
Discount: -10.0%
Price: €164.02
You save: €18.22
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