Antibodies

PLVAP

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against other
Clone MECA-32
Applications FC, IHC
Amount 0.1 mg
ArtNr 20-783-310592
Available
Genway ID:
GWB-5B30C7
Specificity:
PLVAP
Specificity:
PLVAP
Clone:
MECA-32
Fusion Partner:
Spleen cells from immunised rat were fused with cells of the Sp2/0 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Suggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Suggested
Dilution:
Immunohistology - Frozen - Neat - 1/10
Function:
Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.
Subunit:
Homodimer (By similarity).
Subcellular Location:
Cell membrane caveola; Single-pass type II membrane protein (By similarity). Cytoplasm perinuclear region (By similarity). Note=Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region (By similarity).
Tissue Specificity:
Expressed in lung kidney heart aorta placenta muscle pituitary gland adrenals mammary gland bladder lymph node bone marrow trachea digestive tract liver and tumor-associated endothelium.
Induction:
By PMA or VEGF in endothelial cell culture. 1. Hallman. R. et al. (1995) Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier. 2. Carson-Walter. E. B. et al. (2005) Plasmalemmal vesicle associated Protein-1 is a novel marker implicated in brain tumor angiogenesis.
Amount: 0.1 mg
Available: In stock
Listprice: €238.23
Price: €238.23
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