CD137


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	JG1. 6A
Applications	FC, ELISA
Amount	0.025 mg
Item no.	20-783-310625
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-6CC192
Specificity:	CD137NCBI
Gene ID:	3604
Specificity:	CD137
Clone:	JG1. 6A
Immunogen:	Recombinant human CD137-Fc
Fusion Partner:	Lymph node cells from immunised Lou rat were fused with cells of the mouse NS-1 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3) Suggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Function:	Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation.
Subunit:	Interacts with TRAF1 TRAF2 and TRAF3. Interacts with LRR-repeat protein 1/LRR-1.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Expressed on the surface of activated T-cells.
Similarity:	Contains 4 TNFR-Cys repeats. 1. Pollok. K. E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function. 2. Alderson. M. R. et al. (1994) Molecular and biological characterization of human 4-1BB and its ligand. 3. Schwarz. H. et al. (1997) CD137. a member of the tumor necrosis factor receptor family. is located on chromosome 1p36. in a cluster of related genes. and colocalizes with several malignancies. 4. Cannons. J. L. et al. (2001) 4-1BB ligand induces cell division. sustains survival. and enhances effector function of CD4 and CD8 T cells with similar efficacy.

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Amount: 0.025 mg

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Delivery expected until 5/9/2024