CD137

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone JG1. 6A
Applications FC, ELISA
Amount 0.025 mg
ArtNr 20-783-310625
Available
Genway ID:
GWB-6CC192
Specificity:
CD137NCBI
Gene ID:
3604
Specificity:
CD137
Clone:
JG1. 6A
Immunogen:
Recombinant human CD137-Fc
Fusion Partner:
Lymph node cells from immunised Lou rat were fused with cells of the mouse NS-1 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide (NaN3) Suggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Function:
Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation.
Subunit:
Interacts with TRAF1 TRAF2 and TRAF3. Interacts with LRR-repeat protein 1/LRR-1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed on the surface of activated T-cells.
Similarity:
Contains 4 TNFR-Cys repeats. 1. Pollok. K. E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function. 2. Alderson. M. R. et al. (1994) Molecular and biological characterization of human 4-1BB and its ligand. 3. Schwarz. H. et al. (1997) CD137. a member of the tumor necrosis factor receptor family. is located on chromosome 1p36. in a cluster of related genes. and colocalizes with several malignancies. 4. Cannons. J. L. et al. (2001) 4-1BB ligand induces cell division. sustains survival. and enhances effector function of CD4 and CD8 T cells with similar efficacy.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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