Comparison

CD3

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone 145-2C11
Applications FC
Amount 0.025 mg
Item no. 20-783-310631
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-4E7AC0
Specificity:
CD3NCBI
Gene ID:
12501
Specificity:
CD3
Clone:
145-2C11
Immunogen:
H-2Kb - specific mouse cytoxic T lymphocyte clone BM10-37.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 2
Preservative Stabilisers:
0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Suggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (/).
Function:
The CD3 complex mediates signal transduction.
Subunit:
The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma delta epsilon zeta and eta.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Similarity:
Contains 1 ITAM domain. 1. Leo. O. et al. (1987) Identification of a monoclonal antibody specific for a murine T3 polypeptide. 2. Payer. E. et al. (1991) Circulating CD3+/T cell receptor V ³ 3+ fetal murine thymocytes home to the skin and give rise to proliferating dendritic epidermal T cells. J. Immunol. 146: 2536-2543. 3. Salvadori. S. et al. (1994) Abnormal signal transduction by T cells of mice with parental tumors is not seen in mice bearing IL-2-secreting tumors. 4. Tilley. S. L. et al. (2007) Retinoid-related orphan receptor ³ controls immunoglbulin production and the Th1/Th2 cytokine balance in the adaptive immune response to allergen. J. Immunol. 178: 3208-3218. 5. Podd. B. S. et al. (2006) T cells in cryptopatch aggregates share TCR ³ variable region junction sequences with ³ ´ T cells in the small intestinal epithelium of mice. J. Immunol. 176: 6532-6542.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.025 mg
Available: In stock
available

Delivery expected until 4/25/2024 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close