CD35


Manufacturer	GENWAY
Category	Oncology Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	E11
Applications	FC
Amount	0.025 mg
Item no.	20-783-310696
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-A7711D
Specificity:	CD35NCBI
Gene ID:	1378
Specificity:	CD35
Clone:	E11
Immunogen:	Human acute monocytic leukaemia cells
Fusion Partner:	Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Preparation:	Purified IgG prepared by ion exchange chromatography
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide1%Bovine Serum AlbuminSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - Neat
Function:	Mediates cellular binding of particles and immune complexes that have activated complement.
Subunit:	Monomer.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Present on erythrocytes leukocytes glomerular podocytes and splenic follicular dendritic cells.
Polymorphism:	CR1 contains a system of antigens called the Knops blood group system. Polymorphisms within this system are involved in malarial rosetting a process associated with cerebral malaria the major cause of mortality in Plasmodium falciparum malaria. Common Knops system antigens include McCoy (McC) and Sl(a)/Vil (Kn4 or Swain-Langley; Vil or Villien). Sl(a-) phenotype is more common in persons of African descent and may protect against fatal malaria.
Miscellaneous:	This is the sequence of the F allotype of CR1.
Similarity:	Belongs to the receptors of complement activation (RCA) family.
Similarity:	Contains 30 Sushi (CCP/SCR) domains. 1. Hogg. N. et al. (1984) Identification of an anti-monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1). 2. Yoshino. N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts. cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. 3. Birmingham. D. J. et al. (1996) The baboon erythrocyte complement receptor is a glycophosphatidylinositol-linked protein encoded by a homologue of the human CR1-like genetic element 4. Sopper. S. et al. (1997) Lymphocyte subsets and expression of differentiation markers in blood and lymphoid organs of Rhesus monkeys. Cytometry 29: 351-362.

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Amount: 0.025 mg

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Delivery expected until 5/30/2024