CD103

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone 2G5. 1
Applications FC, IP, IHC
Amount 0.025 mg
ArtNr 20-783-310706
Available
Genway ID:
GWB-8EB5AD
Specificity:
CD103NCBI
Gene ID:
3682
Specificity:
CD103
Clone:
2G5. 1
Immunogen:
Human Intestinal lymphocyte
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line. Histology: Intestine
Preparation:
Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium Azide0. 1%Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 5 x 105 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1:50 - 1:100Immunohistology - Frozen - 1:50 - 1:100
Function:
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Subunit:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Domain:
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Similarity:
Belongs to the integrin alpha chain family.
Similarity:
Contains 5 FG-GAP repeats.
Similarity:
Contains 1 VWFA domain. 1. Cerf-Bensussan. N. et al. (1987) A monoclonal antibody (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes. 2. Cerf-Bensussan. N. et al. (1986) A monoclonal antibody specific for rat intestinal lymphocytes. 3. Sopper. S. et al. (1997) Lymphocyte subsets and expression of different markers in blood and lymphoid organs of rhesus monkeys. 4. Yoshino. N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts. cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies.
Amount: 0.025 mg
Available: In stock
Listprice: €152.38
Discount: -10.0%
Price: €137.14
You save: €15.24
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