Antibodies

MOUSE ANTI RAT CD62L

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against Rat
Amount 0.1 mg
Host Mouse
ArtNr 20-783-314567
Available
Genway ID:
GWB-533882
Specificity:
CD62L
Isotype:
IgG1
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium AzideApprox. Protein Concentrations: IgG concentration 1 mg/ml
Specificity:
Recognises rat L-selectin (CD62L). In rats CD62L is expressed by a subset of thymocytes predominantly single positive CD4 or CD8 cells. Expression of rat CD62L is weak and sensitive detection systems (e. g. 3 layer biotin - streptavidin techniques) are recommended on some tissues. Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROLRecommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgG1Goat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L)
Function:
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia By similarity. Subunit structureInteraction with PSGL1/SELPLG is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan and tyrosine sulfation modifications of PSGL1 By similarity. Subcellular locationMembrane; Single-pass type I membrane protein. Tissue specificityExpressed in peripheral blood mononuclear cells (PBMC) spleen and thymus. Ref. 1Induction: Down-regulated by mitogen stimulation of PBMC and spleen T-cells. Ref. 1Sequence similaritiesBelongs to the selectin/LECAM family. Contains 1 C-type lectin domain. Contains 1 EGF-like domain. Contains 2 Sushi (CCP/SCR) domains.
Amount: 0.1 mg
Available: In stock
Listprice: €212.88
Price: €212.88
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